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Irritable Bowel Syndrome

Irritable bowel syndrome or IBS describes a pattern of constant abdominal pain causing gastrointestinal symptoms like increased gas, diarrhea, constipation, bloating and intestinal cramps. People experiencing frequent abdominal pain normally have visceral hypersensitivity in the sensory nerve endings of the intestinal wall, meaning that these people might feel strong reactions to food ingestion, like stretching of the intestine during and after a meal.

CNR1

This gene encodes a protein that is involved in the immune defense system located in the colon as well as the muscular system within the colon. Certain variations of this gene are linked to a change in “colon transit” timing, the speed at which food/stools passes through the colon.