Do I genetically have a bigger appetite than others?


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What we eat will affect why we eat so often. Usually after we eat meals high in fat, our system will not work that well, because the hunger hormone will not be properly ‘switched off’. This breakdown in the body’s internal communication system leads to eating more calories, storing them as fat.

Genetic factors also play a role in interfering with this communication process. For instance, Leptin (LEP) is a protein produced primarily by fat cells, also known as adipocytes, and it acts as a satiety or “full” signal after eating. Certain mutations affect the function of this protein, resulting in a reduced satiety signal after meals, which likely leads to overeating.